Negative sacral slope exists in Chinese Han patients with ankylosing
spondylitis and thoracolumbar kyphosis, with severe kyphosis and a
pronounced femoral shaft tilting as the most likely causes, according to
study findings.
Researchers retrospectively reviewed data for
106 Chinese Han patients with ankylosing spondylitis with thoracolumbar
kyphosis treated between October 2005 and October 2010. The researchers
then analyzed 41 patients for whom lateral radiographs clearly showed
the upper-third of the femur.
Patients were separated into groups by those
who had a sacral slope of less than 0° (group A) and those who had a
sacral slope of 0° or greater (group B). All patients had eight
different sagittal parameters measured, and correlations between the
sagittal parameters, femoral obliquity angle and sacral slopes were
analyzed.
The researchers found patients in group A had significantly larger mean global kyphosis, lumbar lordosis, pelvic tilt, sagittal vertical axis and femoral obliquity angle compared with group B. However, group A also had significantly smaller pelvic incidence and sacral slope.
Although global kyphosis, lumbar lordosis, pelvic tilt and sagittal vertical axis were found to be significantly negatively associated with sacral slope, they were positively associated with femoral obliquity angle, according to the researchers. Pelvic incidence was found to be significantly positively associated with the sacral slope but negatively associated with the femoral obliquity angle.
The researchers found femoral obliquity angle and sacral slope had a significantly negative association.
http://jbjs.org/content/96/22/e188
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